Aside from the access control and transport security concerns of DICOM and non-DICOM network protocols, each protocol may have additional vulnerabilities, and considerations and warnings related to the implementation and use of the protocol. The specific details of any such considerations are outside the scope of DICOM.

An implementation that supports direct file access using non-DICOM protocols should incorporate mechanisms mitigating the particular risks from those protocols. This includes supply chain protection for software components, update and patching mechanisms, site-specific configuration differing from the default, and other administrative issues.