Ex-vivo image acquisition is conceptually the same as in-vivo. Both macroscopic camera and confocal microscope are mounted inside the same housing. The excised tissue is placed on a glass microscope slide, then the slide is placed on the ex-vivo confocal microscope. The stage positions the slide firstly centered over the macroscopic camera and then centered over the confocal microscope. Once the imaging is done, the tissue is either processed or stored, and the slide is discarded.