CID 4109 Model-Independent Dynamic Contrast Analysis Parameter

CID 4109 Model-Independent Dynamic Contrast Analysis Parameter (Current)
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Keyword:: ModelIndependentDynamicContrastAnalysisParameter
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Table CID 4109. Model-Independent Dynamic Contrast Analysis Parameter

Coding Scheme Designator	Code Value	Code Meaning	Units
DCM	126320	IAUC	DT (mmol/l.s, UCUM, "mmol/l.s")
DCM	126321	IAUC60	DT (mmol/l.s, UCUM, "mmol/l.s")
DCM	126322	IAUC90	DT (mmol/l.s, UCUM, "mmol/l.s")
DCM	126323	IAUC180	DT (mmol/l.s, UCUM, "mmol/l.s")
DCM	126324	IAUCBN	DT {normalized}, UCUM, "normalized"
DCM	126325	IAUC60BN	DT {/AIF}, UCUM, "/AIF"
DCM	126326	IAUC90BN	DT {/AIF}, UCUM, "/AIF"
DCM	126327	IAUC180BN	DT {/AIF}, UCUM, "/AIF"
DCM	126370	Time of Peak Concentration	DT (s, UCUM, "s")
DCM	126372	Time of Leading Half-Peak Concentration	DT (s, UCUM, "s")
DCM	126371	Bolus Arrival Time	DT (s, UCUM, "s")
DCM	113069	Time To Peak	DT (s, UCUM, "s")
DCM	126374	Temporal Derivative Threshold
DCM	126375	Maximum Slope
DCM	126376	Maximum Difference
DCM	126377	Tracer Concentration	DT (mmol/l, UCUM, "mmol/l")

Note

(126326, DCM, "IAUC90BN") can be used for DCE-MRI using a Gd-based contrast agent to represent the IAUGC_BN measurement in the claim of the QIBA DCE MRI Quantification Profile, though the concept itself is not specific to the modality or the contast agent used. See http://www.rsna.org/QIBA_Protocols_and_Profiles.aspx. See also Ng, CS., et al. "Reproducibility of Perfusion Parameters in Dynamic Contrast-Enhanced MRI of Lung and Liver Tumors: Effect on Estimates of Patient Sample Size in Clinical Trials and on Individual Patient Responses." AJR 194, no. 2 (February 1, 2010): W134-40. http://dx.doi.org/10.2214/AJR.09.3116.

The type of contrast agent and the AIF used for blood normalization may or may not be post-coordinated.

E.g., voxel-wise IAUC_BN measurements encoded as a parametric map with the quantity defined by the Quantity Definition Sequence (0040,9220) in a Real World Value Map might be encoded as:

(246205007, SCT, "Quantity") = (126326, DCM, "IAUC90BN")

(370129005, SCT, "Measurement Method") = (126362, DCM, "User-defined AIF ROI")

(123011, DCM, "Contrast Bolus/Agent") = (58281002, SCT, "Gadolinium")

E.g., an IAUC_BN measurement for an ROI encoded in a structured report might be encoded as:

NUM (126326, DCM, "IAUC90BN") = 0.230 (UNITS = ({normalized}, UCUM, "normalized")

>HAS CONCEPT MOD: CODE (370129005, SCT, "Measurement Method") = (126364, DCM, "Blind Estimation of AIF")

Note that the generic ROI measurement templates do not have the contrast/bolus agent as a parameter; this may be implicit from context, or inherited from the (121058, DCM,"Procedure reported") in the parent template.

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