The description of the need addressed by the Application Profile (e.g., cardiac, echography, angiography) and its context of application;

The selection, at the Data Format Layer, of a number of specific IODs and associated SOP Classes. For standard DICOM SOP Classes, this shall be done by reference to PS3.4. These SOP Classes, like any other DICOM SOP Classes are assigned a unique registered UID. For each SOP Class it shall be stated if its support is required or optional within the context of this profile;

The selection of a specific Media Format definition. This is done by reference to PS3.12 that specify the selected Physical Medium, a specific associated Media Format and the mapping of this Media Format (or file system) services onto the DICOM File Service;

The selection of appropriate Transfer Syntaxes;

The selection of a specific Security Profile. This is done by reference to PS3.15 that specifies the cryptographic algorithms to be used to encapsulate the DICOM Files of the DICOM File Set into Secure DICOM Files. If a Media Storage Application Profile selects no Security Profile, then the Application Profile is unsecure and the Secure DICOM File Format shall not be used with that Application Profile;

Other choices facilitating interoperability such as specific limits (e.g., maximum file sizes, if necessary, support of options, if any).