In order to deliver a Brachytherapy treatment fraction described in an RT Plan IOD, the RT Brachy Application Setup Delivery Instruction IOD describes which part of the RT Plan is to be delivered and contains additional parameters. This information is supplied by a Treatment Management System (TMS) when it creates an RT Brachy Application Setup Delivery Instruction SOP Instance which is referenced by a Unified Procedure Step (UPS) in the Unified Worklist and Procedure Step model.