Rationale for Correction:Larger patients are not accurately described by the conventional (James) LBM formula, and an alternative formula has been defined with more robust characteristics across a larger range of patient sizes.Add appropriate codes for the additional formula both for the SUV Type attribute used in images and the corresponding concepts used in real World Value Maps and Structured Reports, and link the enumerated values for SUV Type to the PS3.16 concept definitions.Also correct the order of curly braces unit annotations (annotations need to follow, not precede, the units if not unity).Also change the reference to CID 84 to CID 85,. since SUV units have been factored out of PET units into their own context group.The existing Enumerated Value for LBM by the James method is not renamed due to the potential impact on the installed base.
Correction Wording:
Amend PS 3.3:
PET Series Module contains IOD Attributes that describe a PET Series.
PET Series Module Attributes
Attribute Name
Tag
Type
Attribute Description
...
...
...
...
SUV Type
(0054,1006)
3
Type of Standardized Uptake Value (SUV).Enumerated Values:BSAbody surface areaBWbody weightLBMlean body mass by James methodLBMJANMAlean body mass by Janmahasatian methodIBWideal body weightIf absent, and the Units (0054,1001) are GML, then the type of SUV shall be assumed to be BW.The type of SUV cannot reliably be deduced from the units alone, i.e., SUVbw, SUVibw and SUVlbm (James or Janmahasatian)all have units of GML.
...
...
...
..
The formulas for the determination of SUVbw, SUVbsa, SUVlbm(James) and SUVibw are defined in Sugawara et al. Reevaluation of the Standardized Uptake Value for FDG: Variations with Body Weight and Methods for Correction. Radiology, 1999 at .
The Janmahasatian LBM formula is defined in Janmahasatian et al. Quantification of Lean Bodyweight. Clin Pharmacokinet. 2005 Oct 1;44(10):1051–65. at
and its role in SUVlbm(Janma) calculation is discussed in Tahari et al. Optimum Lean Body Formulation for Correction of Standardized Uptake Value in PET Imaging. Journal of Nuclear Medicine. 2014 Sep 1;55(9):1481–4. at .
See also
.
Amend DICOM PS 3.16:
PET UnitsType:ExtensibleVersion:20141110
PET Units
Coding Scheme Designator
Code Value
Code Meaning
Include
UCUM
{counts}
Counts
UCUM
{counts}/s
Counts per second
UCUM
{propcounts}
Proportional to counts
UCUM
{propcounts}/s
Proportional to counts per second
UCUM
cm2
Centimeter**2
UCUM
%
Percent
UCUM
Bq/ml
Becquerels/milliliter
UCUM
mg/min/ml
Milligrams/minute/milliliter
UCUM
umol/min/ml
Micromole/minute/milliliter
UCUM
ml/min/g
Milliliter/minute/gram
UCUM
ml/g
Milliliter/gram
UCUM
/cm
/Centimeter
UCUM
umol/ml
Micromole/milliliter
SUV UnitsType:ExtensibleVersion:20141110
SUV Units
Coding Scheme Designator
Code Value
Code Meaning
UCUM
{SUVbw}g/ml{SUVbw}
Standardized Uptake Value body weight
UCUM
{SUVlbm}g/ml{SUVlbm}
Standardized Uptake Value lean body mass (James)
UCUM
g/ml{SUVlbm(Janma)}
Standardized Uptake Value lean body mass (Janma)
UCUM
{SUVbsa}cm2/ml{SUVbsa}
Standardized Uptake Value body surface area
UCUM
{SUVibw}g/ml{SUVibw}
Standardized Uptake Value ideal body weight
The formulas for the determination of SUVbw, SUVbsa, SUVlbm(James) and SUVibw are defined in Sugawara et al. Reevaluation of the Standardized Uptake Value for FDG: Variations with Body Weight and Methods for Correction. Radiology, 1999 at . The Janmahasatian LBM formula is defined in Janmahasatian et al. Quantification of Lean Bodyweight. Clin Pharmacokinet. 2005 Oct 1;44(10):1051–65. at and its role in SUVlbm(Janma) calculation is discussed in Tahari et al. Optimum Lean Body Formulation for Correction of Standardized Uptake Value in PET Imaging. Journal of Nuclear Medicine. 2014 Sep
1;55(9):1481–4. at .The patient size correction factors are summarized here, where weight is in kg and height is in cm:SUVbw: males & females: weightSUVlbm(James): males: 1.10 * weight - 120 * (weight/height) ^2females: 1.07 * weight - 148 * (weight/height) ^2SUVlbm(Janma): males: 9.27E3 * weight / (6.68E3 + 216 * weight / (height^2))females: 9.27E3 * weight / (8.78E3 + 244 * weight / (height^2))SUVbsa: males & females: weight^ 0.425 * height^0.725 * 0.007184SUVibw: males: 48.0 + 1.06 * (height - 152)females: 45.5 + 0.91 * (height - 152)Abstract Multi-dimensional Image Model Component SemanticsType:ExtensibleVersion:20141110
Abstract Multi-dimensional Image Model Component Semantics
Coding Scheme Designator
Code Value
Code Meaning
SNOMED-CT Concept ID
UMLS Concept Unique ID
...
...
...
DCM
126400
Standardized Uptake Value
DCM
126401
SUVbw
DCM
126402
SUVlbm
DCM
126405
SUVlbm(Janma)
DCM
126403
SUVbsa
DCM
126404
SUVibw
Amend DICOM PS3.16 concept definitions:
DICOM Controlled Terminology Definitions
Code Value
Code Meaning
Definition
Notes
126400
Standardized Uptake Value
A ratio of locally measured radioactivity concentration versus the injected radioactivity distibuted evenly throughout the whole body.This general concept encompasses all specific methods of calculating the whole body volume of distribution, such as using body weight, lean body mass, body surface area, etc.
126401
SUVbw
Standardized Uptake Value calculated using body weight. The patient size
correction factor for males and females is body weight.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126402
SUVlbm
Standardized Uptake Value calculated using lean body mass by James method. The patient size correction factor for males is 1.10 * weight - 120 * (weight/height) ^2, and for females is 1.07 * weight - 148 * (weight/height) ^2.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126403
SUVbsa
Standardized Uptake Value calculated using body surface area. The patient size
correction factor for males and females is weight^ 0.425 * height^0.725 *
0.007184.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126404
SUVibw
Standardized Uptake Value calculated using ideal body weight. The patient size
correction factor for males is 48.0 + 1.06 * (height - 152) and for females is 45.5
+ 0.91 * (height - 152).Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126405
SUVlbm(Janma)
Standardized Uptake Value calculated using lean body mass by Janmahasatian method. The patient size correction factor for males is 9.27E3 * weight / (6.68E3 + 216 * weight / (height^2)) and for females is 9.27E3 * weight / (8.78E3 + 244 * weight / (height^2)).Defined in Janmahasatian et al. Quantification of Lean Bodyweight. Clin Pharmacokinet. 2005 Oct 1;44(10):1051–65. at and its role in SUVlbm(Janma) calculation is discussed in Tahari et al. Optimum Lean Body Formulation for Correction of Standardized Uptake Value in PET Imaging. Journal of Nuclear Medicine. 2014 Sep 1;55(9):1481–4. at .
126410
SUV body weight calculation method
Method of calculating Standardized Uptake Value using body weight. The patient
size correction factor for males and females is body weight.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126411
SUV lean body mass calculation method
James mMethod of calculating Standardized Uptake Value using lean body mass. The patient size correction factor for males is 1.10 * weight - 120 * (weight/height) ^2, and for females is 1.07 * weight - 148 * (weight/height) ^2.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126412
SUV body surface area calculation method
Method of calculating Standardized Uptake Value using body surface area. The
patient size correction factor for males and females is weight^ 0.425 * height^0.725
* 0.007184.Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126413
SUV ideal body weight calculation method
Method of calculating Standardized Uptake Value using ideal body weight. The
patient size correction factor for males is 48.0 + 1.06 * (height - 152) and for
females is 45.5 + 0.91 * (height - 152).Defined in
Sugawara et al. Reevaluation of the Standardized Uptake Value for
FDG: Variations with Body Weight and Methods for Correction.Radiology, 1999
at
126414
SUV lean body mass calculation Janmahasatian method
Janmahasatian method of calculating Standardized Uptake Value using lean body mass. The patient size correction factor for males is 9.27E3 * weight / (6.68E3 + 216 * weight / (height^2)) and for females is 9.27E3 * weight / (8.78E3 + 244 * weight / (height^2)).Defined in Janmahasatian et al. Quantification of Lean Bodyweight. Clin Pharmacokinet. 2005 Oct 1;44(10):1051–65. at and its role in SUVlbm(Janma) calculation is discussed in Tahari et al. Optimum Lean Body Formulation for Correction of Standardized Uptake Value in PET Imaging. Journal of Nuclear Medicine. 2014 Sep 1;55(9):1481–4. at .