Radiopharmaceutical Radiation Dose SR IOD Templates 

The templates that comprise the Radiopharmaceutical Radiation Dose SR are interconnected as in Figure A-17.

Radiopharmaceutical Radiation Dose SR IOD Template Structure

Figure A-17. Radiopharmaceutical Radiation Dose SR IOD Template Structure


TID 10021 Radiopharmaceutical Radiation Dose

This template defines a container (the root) with subsidiary content items, each of which corresponds to a single Radiopharmaceutical Administration Dose event entry. There is a defined recording observer (the system and/or person responsible for recording the assay of the radiopharmaceutical, and the person administered the radiopharmaceutical). Multiple Radiopharmaceutical Radiation Dose objects may be created for one study. Radiopharmaceutical Start DateTime in TID 10022 “Radiopharmaceutical Administration Event Data” will convey the order of administrations.

Type:

Extensible

Order:

Significant

Root:

Yes

Table TID 10021. Radiopharmaceutical Radiation Dose

NL

Rel with Parent

VT

Concept Name

VM

Req Type

Condition

Value Set Constraint

1

CONTAINER

EV (113500, DCM, "Radiopharmaceutical Radiation Dose Report")

1

M

2

>

HAS CONCEPT MOD

CODE

EV (G-C2D0, SRT, "Associated Procedure")

1

M

DCID 3108 “NM/PET Procedures”

3

>>

HAS CONCEPT MOD

CODE

EV (G-C0E8, SRT, "Has Intent")

1

M

DCID 3629 “Procedure Intent”

4

>

CONTAINS

INCLUDE

DTID 10022 “Radiopharmaceutical Administration Event Data”

1

M

5

>

CONTAINS

INCLUDE

DTID 10024 “Radiopharmaceutical Administration Patient Characteristics”

1

U

6

>

CONTAINS

TEXT

EV (121106, DCM, "Comment")

1

U


Content Item Descriptions

Row 2

The associated procedure is the procedure performed, or if no procedure was performed the procedure that was ordered.

TID 10022 Radiopharmaceutical Administration Event Data

The Radiopharmaceutical Administration Event conveys the dose and assay and time information of a single radiopharmaceutical event. A Radiopharmaceutical Administration event is one radioactive pharmaceutical administered to a patient.

Type:

Extensible

Order:

Significant

Table TID 10022. Radiopharmaceutical Administration Event Data

NL

Rel with Parent

VT

Concept Name

VM

Req Type

Condition

Value Set Constraint

1

CONTAINER

EV (113502, DCM, "Radiopharmaceutical Administration")

1

M

2

>

CONTAINS

CODE

EV (F-61FDB, SRT, "Radiopharmaceutical agent")

1

M

DCID 25 “Radiopharmaceuticals”

DCID 4021 “PET Radiopharmaceutical”

3

>>

HAS PROPERTIES

CODE

EV (C-10072, SRT, "Radionuclide")

1

M

DCID 18 “Isotopes in Radiopharmaceuticals”

DCID 4020 “PET Radionuclide”

4

>>

HAS PROPERTIES

NUM

EV (R-42806, SRT, "Radionuclide Half Life")

1

M

UNITS = EV (s, UCUM, "seconds")

5

>

CONTAINS

NUM

EV (123007, DCM, "Radiopharmaceutical Specific Activity")

1

U

UNITS = EV (Bq/mmol, UCUM, "Bq/mmol")

6

>

CONTAINS

UIDREF

EV (113503, DCM, "Radiopharmaceutical Administration Event UID")

1

M

7

>

CONTAINS

CODE

EV (113505, DCM, "Intravenous Extravasation Symptoms")

1-n

U

DCID 10043 “Intravenous Extravasation Symptoms”

8

>

CONTAINS

NUM

EV (113506, DCM, "Estimated Extravasation Activity")

1

U

UNITS = EV(%, UCUM, "percent")

9

>

CONTAINS

DATETIME

EV (123003, DCM, "Radiopharmaceutical Start DateTime")

1

M

10

>

CONTAINS

DATETIME

EV (123004, DCM, "Radiopharmaceutical Stop DateTime")

1

U

11

>

CONTAINS

NUM

EV (113507, DCM, "Administered activity")

1

M

UNITS = EV (MBq, UCUM, "MBq")

12

>

CONTAINS

NUM

EV (123005, DCM, "Radiopharmaceutical Volume")

1

U

UNITS = EV (cm3, UCUM, "cm3")

13

>

CONTAINS

NUM

EV (113508, DCM, "Pre-Administration Measured Activity")

1

U

UNITS = EV (MBq, UCUM, "MBq")

14

>>

HAS OBS CONTEXT

CODE

EV (113540, DCM, "Activity Measurement Device")

1

U

DCID 10041 “Source of Radioisotope Activity Information”

15

>>

HAS OBS CONTEXT

INCLUDE

DTID 1002 “Observer Context”

1-n

U

16

>

CONTAINS

NUM

EV (113509, DCM, "Post-Administration Measured Activity")

1

U

UNITS = EV (MBq, UCUM, "MBq")

17

>>

HAS OBS CONTEXT

CODE

EV (113540, DCM, "Activity Measurement Device")

1

U

DCID 10041 “Source of Radioisotope Activity Information”

18

>>

HAS OBS CONTEXT

INCLUDE

DTID 1002 “Observer Context”

1-n

U

19

>

CONTAINS

INCLUDE

DTID 10023 “Organ Dose”

1-n

U

20

>

CONTAINS

CODE

EV (G-C340, SRT, "Route of administration")

1

M

BCID 11 “Route of Administration”

21

>>

HAS PROPERTIES

CODE

EV (G-C581, SRT, "Site of")

1

MC

IF Row 22 equals (G-D101, SRT, "Intravenous route") or (G-D103, SRT, "Intramuscular route")

DCID 3746 “Percutaneous Entry Site”

22

>>>

HAS CONCEPT MOD

CODE

EV (G-C171, SRT, "Laterality")

1

MC

IF Row 23 has laterality

DCID 244 “Laterality”

23

>

HAS OBS CONTEXT

INCLUDE

DTID 1020 “Person Participant”

1-n

M

$PersonProcedureRole = EV (113851, DCM, "Irradiation Administering")

24

>

CONTAINS

CODE

EV (121147, DCM, "Billing Code(s) ")

1-n

U

25

>

CONTAINS

CODE

EV (113510, DCM, "Drug Product Identifier")

1-n

U

26

>

CONTAINS

TEXT

EV (111529, DCM, "Brand Name")

1

U

27

>

CONTAINS

TEXT

EV (113511, DCM, "Radiopharmaceutical Dispense Unit Identifier")

1

U

28

>>

CONTAINS

TEXT

EV (113512, DCM, "Radiopharmaceutical Lot Identifier")

1-n

U

29

>>

CONTAINS

TEXT

EV (113513, DCM, "Reagent Vial Identifier")

1-n

U

30

>>

CONTAINS

TEXT

EV (113514, DCM, "Radionuclide Identifier")

1-n

U

31

>

CONTAINS

TEXT

EV (113516, DCM, "Prescription Identifier")

1

U

32

>

CONTAINS

TEXT

EV (121106, DCM, "Comment")

1

U


Content Item Descriptions

Row 4

The value of Half-life that was used for computing the decay of the administered radiopharmaceutical. It is not intended for use by the receiver for any further computation.

Row 5

Activity per unit mass of the radiopharmaceutical at Radiopharmaceutical Start Time

Row 6

Unique identification of a single radiopharmaceutical administration event.

Row 8

The estimated percentage of administered activity lost at the injection site. The estimation includes extravasation, paravenous administration and leakage at the injection site.

Row 9

The time the radiopharmaceutical was administered to the patient for imaging purposes.

Row 11

Total amount of radioactivity administered to the patient at Radiopharmaceutical Start Time. It is a computed field from the TID 10022 Pre-Administration Measured Activity Row 13, TID 10022 Post-Administration Measured Activity Row 17, Radionuclide Half Life Row 4 and Radiopharmaceutical Start Time Row 9.

Does not include estimated extravasation activity.

Rows 13, 16

Observation DateTime (0040,A032) shall be used to record when the measurement was taken.

Row 23

Identifies the person administering the product.

Row 24

The billing codes for the preparation and administration of the radiopharmaceutical. It does not include performance and interpretation of the imaging.

Row 25

Registered drug establishment code for the product. A coding scheme example is NDC, WHO-DDE or RxNorm. Multiple entries can be used for equivalent drug product codes.

Row 27

The human readable identification of the specific radiopharmaceutical quantity (dose) administered to the patient.

Row 28

Identifies the vial, batch or lot number from which the individual radiopharmaceutical quantity (dose) was produced. Row 27 the Radiopharmaceutical Identifier records the identification for each individual dose.

Row 29

Identifies the lot or unit serial number for the reagent component for the radiopharmaceutical identified in row 27.

Row 30

Identifies the lot or unit serial number for the radionuclide component for the radiopharmaceutical identified in row 27.

TID 10023 Organ Dose

This template conveys the information about the dose to a single organ.

Type:

Extensible

Order:

Significant

Table TID 10023. Organ Dose

NL

Rel with Parent

VT

Concept Name

VM

Req Type

Condition

Value Set Constraint

1

CONTAINER

EV (113517, DCM, "Organ Dose Information")

1

M

2

>

HAS CONCEPT MOD

CODE

EV (G-C0E3, SRT, "Finding Site")

1

M

DCID 10044 “Radiosensitive Organs”

3

>

HAS CONCEPT MOD

CODE

EV (G-C171, SRT, "Laterality")

1

MC

IFF anatomy has laterality

DCID 244 “Laterality”

4

>

CONTAINS

NUM

EV (G-D701, SRT, "Mass")

1

U

UNITS = EV (g, UCUM, "grams")

5

>>

HAS CONCEPT MOD

TEXT

EV (G-C036, SRT, "Measurement Method")

1

M

6

>

CONTAINS

NUM

EV (113518, DCM, "Organ Dose")

1

M

UNITS = EV (mGy, UCUM, "mGy")

7

>>

HAS PROPERTIES

CODE

EV (121406, DCM, "Reference Authority")

1

MC

XOR Row 8

BCID 10040 “Radiopharmaceutical Organ Dose Reference Authority”

8

>>

HAS PROPERTIES

TEXT

EV (121406, DCM, "Reference Authority")

1

MC

XOR Row 7


Content Item Descriptions

Row 3

For paired organs,use (G-A102, SRT, "Right and Left") to report the estimated absorbed dose for both organs.

Row 4

The estimated mass of organ in grams used when calculating the organ dose.

Row 5

Method used to obtain the estimate. This could include a method that does not involve performing a measurement (e.g., Standard Organ Mass Tables).

Row 6

Organ dose (in units of mGy). Organ is specified by row 2.

TID 10024 Radiopharmaceutical Administration Patient Characteristics

This template describes the characteristics of the patient that are specific to the current clinical presentation (visit). The characteristics noted may affect the activity received, and how dose is calculated for the patient. Patient Characteristic concepts in this template, which may replicate attributes in the Patient Study Module, are included here as possible targets of by-reference relationships from other content items in the SR tree.

Type:

Extensible

Order:

Significant

Table >TID 10024. Radiopharmaceutical Administration Patient Characteristics

NL

Rel with Parent

VT

Concept Name

VM

Req Type

Condition

Value Set Constraint

1

CONTAINER

EV (121118, DCM, "Patient Characteristics")

2

>

CONTAINS

CODE

EV (109054, DCM, "Patient state")

1-n

U

DCID 10045 “Radiopharmaceutical Patient State”

3

>

CONTAINS

NUM

EV (121033, DCM, "Subject Age")

1

U

UNITS = DCID 7456 “Units of Measure for Age”

4

>

CONTAINS

CODE

EV (121032, DCM, "Subject Sex")

1

U

DCID 7455 “Sex”

5

>

CONTAINS

NUM

EV (8302-2, LN, "Patient Height")

1

U

UNITS = EV (cm, UCUM, "cm")

6

>

CONTAINS

NUM

EV (29463-7, LN, "Patient Weight")

1

U

UNITS = EV (kg, UCUM, "kg").

7

>

CONTAINS

NUM

EV (8277-6, LN, "Body Surface Area")

1

U

UNITS = EV (m2, UCUM, "m^2")

8

>>

INFERRED FROM

CODE

EV (8278-4, LN, "Body Surface Area Formula")

1

U

BCID 3663 “Body Surface Area Equations”

9

>

CONTAINS

NUM

EV (F-01860, SRT, "Body Mass Index")

1

U

UNITS = EV (kg/m2, UCUM, "kg/m^2")

10

>>

INFERRED FROM

CODE

EV (121420, DCM, "Equation")

1

U

DT (122265, DCM, "BMI = Wt/Ht^2")

11

>

CONTAINS

NUM

EV (14749-6, LN, "Glucose")

1

U

UNITS = EV ("mmol/l", UCUM, "mmol/l")

12

>

CONTAINS

NUM

EV(113550, DCM, "Fasting Duration")

1

U

UNITS = DT (h, UCUM, "hours")

13

>

CONTAINS

NUM

EV(113551, DCM, "Hydration Volume")

1

U

UNITS = DT (ml, UCUM, "ml")

14

>

CONTAINS

TEXT

EV (113552, DCM, "Recent Physical Activity")

1

U

15

>

CONTAINS

NUM

EV (2160-0, LN, "Serum Creatinine")

1

U

UNITS = DT (mg/dl, UCUM, "mg/dl")

16

>

CONTAINS

NUM

EV (F-70210, SRT, "Glomerular Filtration Rate")

1-n

U

UNITS = DT (ml/min{1.73_m2}, UCUM, "ml/min/1.73m2")

17

>>

HAS CONCEPT MOD

CODE

EV (G-C036, SRT, "Measurement Method")

1

U

DCID 10047 “GFR Measurement Methods”

18

>>

HAS CONCEPT MOD

CODE

EV (121050, DCM, "Equivalent meaning of concept name")

1

M

DCID 10046 “GFR Measurements”


Content Item Descriptions

Row 3

Defaults to value of Patient's Age (0010,1010) in Patient Study Module

Row 5

Patient height may differ from Patient's Size (0010,1020). Row 4 is the height value used for any height based protocols.

Observation DateTime (0040,A032) may be used to record when the measurement was taken.

Row 6

Patient weight may differ from Patient's Weight (0010,1030). Row 5 is the weight value used for any weight based protocols.

Observation DateTime (0040,A032) shall be used to record when the measurement was taken.

Row 11

Patient's Blood Glucose level.

Observation DateTime (0040,A032) shall be used to record when the measurement was taken.

Row 15

Serum Creatinine level.

Observation DateTime (0040,A032) shall be used to record when the measurement was taken.

Row 16

Glomerular Filtration Rate Observation DateTime (0040,A032) shall be used to record when the measurement was taken.

The formatting of the UCUM units is aligned with LOINC. See http://unitsofmeasure.org/trac/ticket/98