OOO.3 Real-World Radiopharmaceutical and Radiopharmaceutical Components Identification

The Radiopharmaceutical Radiation Dose (RRD) template provides a means to report the radiopharmaceutical identification number and the identification numbers of its components.

A typical use case is that when a radio-pharmacist elutes a radionuclide from a generator into a vial. The radionuclide elution is given an identification number (Radionuclide Vial Identifier). The pharmacists then draws some radionuclide from the vial to compound with a reagent (Reagent Vial Identifier) creating a multidose vial of a radiopharmaceutical. The multidose vial is given identification number (Radiopharmaceutical Lot Identifier). Individual doses are drawn from the multidose vial for administration to patients. Each of the doses is given an identification number (Radiopharmaceutical Identifier).

A second use case is that when a patient is prescribed 2 MBq of an oral radiopharmaceutical. The radio-pharmacist dispenses two 1 MBq capsules. Each capsule may have different lot number (Radiopharmaceutical Lot Identifier). The two capsules are administered at the same time as one dose (Radiopharmaceutical Identifier). The report may contain two Radiopharmaceutical Lot Identifiers one for each capsule and one radiopharmaceutical identifier for the dose.

Figure OOO-7 is a diagram the displays the hierarchical relationship between the radiopharmaceutical dispense unit identifier, radiopharmaceutical lot identifier, reagent vial identifier and the radionuclide vial identifier.

Radiopharmaceutical and Radiopharmaceutical Component Identification Relationship

Figure OOO-7. Radiopharmaceutical and Radiopharmaceutical Component Identification Relationship